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Detoxified Lethal Toxin as a Potential Mucosal Vaccine against Anthrax
The nontoxic mutant lethal factor (mLF; which has the E687C substitution) and functional protective antigen (PA63) of Bacillus anthracis were evaluated for their use as mucosal vaccines against anthrax in A/J mice. Intranasal vaccination of three doses of 30 μg of mLF or 60 μg of PA63 elicited signi...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292655/ https://ncbi.nlm.nih.gov/pubmed/18256208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00402-07 |
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