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Detoxified Lethal Toxin as a Potential Mucosal Vaccine against Anthrax

The nontoxic mutant lethal factor (mLF; which has the E687C substitution) and functional protective antigen (PA63) of Bacillus anthracis were evaluated for their use as mucosal vaccines against anthrax in A/J mice. Intranasal vaccination of three doses of 30 μg of mLF or 60 μg of PA63 elicited signi...

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Detalhes bibliográficos
Main Authors: Xu, Qingfu, Zeng, Mingtao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292655/
https://ncbi.nlm.nih.gov/pubmed/18256208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00402-07
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