Transcriptional Activation and Increased mRNA Stability Contribute to Overexpression of CDR1 in Azole-Resistant Candida albicans

Many azole-resistant (AR) clinical isolates of Candida albicans display increased expression of the drug transporters CDR1 and CDR2. In this study, we evaluate the molecular mechanisms that contribute to the maintenance of constitutively high CDR1 transcript levels in two matched pairs of azole-susc...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Manoharlal, Raman, Gaur, Naseem Akhtar, Panwar, Sneh Lata, Morschhäuser, Joachim, Prasad, Rajendra
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292549/
https://ncbi.nlm.nih.gov/pubmed/18268086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01106-07
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker