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Binding Cooperativity in Phage λ is Not Sufficient to Produce an Effective Switch
In the wild-type phage λ, binding of CI to O(R)2 helps polymerase bound to P(RM) transition from a closed to open complex. Activators on other promoters increase the polymerase-DNA binding energy, or affect both the binding energy and the closed-open transition probability. Using a validated mathema...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292370/ https://ncbi.nlm.nih.gov/pubmed/18400951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.121756 |
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