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Rapid detection of point mutations of the Neisseria gonorrhoeae gyrA gene associated with decreased susceptibilities to quinolones.

Mutations in the gyrA gene resulting in amino acid changes at Ser-91 and Asp-95 are significantly associated with decreased susceptibilities to quinolones in Neisseria gonorrhoeae. To detect these mutations, we developed a rapid and simple assay based on amplification of the region of the gyrA gene...

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Autors principals: Deguchi, T, Yasuda, M, Nakano, M, Ozeki, S, Ezaki, T, Maeda, S, Saito, I, Kawada, Y
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC229227/
https://ncbi.nlm.nih.gov/pubmed/8862594
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