Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

A fundamental challenge in understanding how dendritic spine morphology controls learning and memory has been quantifying three-dimensional (3D) spine shapes with sufficient precision to distinguish morphologic types, and sufficient throughput for robust statistical analysis. The necessity to analyz...

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Main Authors: Rodriguez, Alfredo, Ehlenberger, Douglas B., Dickstein, Dara L., Hof, Patrick R., Wearne, Susan L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292261/
https://ncbi.nlm.nih.gov/pubmed/18431482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001997
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