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Anti-HIV Activity Mediated by Natural Killer and CD8+ Cells after Toll-Like Receptor 7/8 Triggering

We previously found that triggering TLR7/8 either by single stranded HIV RNA or synthetic compounds induced changes in the lymphoid microenvironment unfavorable to HIV. In this study, we used selective TLR7 and 8 agonists to dissect their contribution to the anti-HIV effects. While triggering TLR7 i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schlaepfer, Erika, Speck, Roberto F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292240/
https://ncbi.nlm.nih.gov/pubmed/18431484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001999
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