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P44-M Calculation of the Isoelectric Point of Tryptic Peptides Based on Adjacent Amino Acid Effects

Current algorithms for the calculation of peptide or protein pI, based solely on the charge associated with individual amino acids, can calculate pI values to within ±0.2pI units. Here we present a new pI calculation algorithm that takes into account the effect of adjacent amino acids on the pI valu...

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Detalhes bibliográficos
Main Authors: Sevinsky, J. R., Cargile, B. J., Essader, A. S., Eu, J. P., Stephenson, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association of Biomolecular Resource Facilities 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291873/
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