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Analysis of Unregulated Formin Activity Reveals How Yeast Can Balance F-Actin Assembly between Different Microfilament-based Organizations

Formins are regulated actin-nucleating proteins that are widespread among eukaryotes. Overexpression of unregulated formins in budding yeast is lethal and causes a massive accumulation of disorganized cable-like filaments. To explore the basis of this lethality, a cDNA library was screened to identi...

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Bibliografiske detaljer
Main Authors: Gao, Lina, Bretscher, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291441/
https://ncbi.nlm.nih.gov/pubmed/18234843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-05-0520
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