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TRPV1 Antagonists Elevate Cell Surface Populations of Receptor Protein and Exacerbate TRPV1-Mediated Toxicities in Human Lung Epithelial Cells

TRPV1 mediates cell death and pro-inflammatory cytokine production in lung epithelial cells exposed to prototypical receptor agonists. This study shows that NHBE, BEAS-2B and TRPV1 over-expressing BEAS-2B cells pre-treated with various TRPV1 antagonists become sensitized to the prototypical TRPV1 ag...

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Autors principals: Johansen, Mark E., Reilly, Christopher A., Yost, Garold S.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291391/
https://ncbi.nlm.nih.gov/pubmed/16120755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfi292
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