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Are pleiotropic effects of statins real?

The clinical benefits of statins are strongly related to their low density lipoprotein-cholesterol (LDL-C) lowering properties. However, because mevalonic acid (MVA), the product of 3-hydroxy-3-methyl-3-glutaryl coenzyme A (HMG-CoA) reductase reaction, is the precursor not only of cholesterol but al...

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Detalhes bibliográficos
Main Authors: Corsini, Alberto, Ferri, Nicola, Cortellaro, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291305/
https://ncbi.nlm.nih.gov/pubmed/18078012
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