Exposure–response analysis reveals that clinically important toxicity difference can exist between bioequivalent carbamazepine tablets

AIMS: To assess whether, using the current regulatory criteria, therapeutically important differences can exist between bioequivalent carbamazepine (CBZ) tablets. A secondary goal was to demonstrate quantitatively the relationship between the risk of neurological adverse effects to orally ingested C...

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Detaylı Bibliyografya
Asıl Yazarlar: Tothfalusi, Laszlo, Speidl, Szilvia, Endrenyi, Laszlo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2008
Konular:
Drug Safety
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291269/
https://ncbi.nlm.nih.gov/pubmed/17711537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02984.x
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