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Limited frequency of the CYP2C19*17 allele and its minor role in a Japanese population

AIMS: We investigated the CYP2C19*17 allelic frequency in Japanese subjects, and evaluated whether CYP2C19*17 is an important determinant of interindividual variability of CYP2C19 activity. METHODS: We enrolled 265 subjects to determine their CYP2C19 genotype and plasma metabolic ratio following a s...

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Hlavní autoři: Sugimoto, Katsuyoshi, Uno, Tsukasa, Yamazaki, Hiroshi, Tateishi, Tomonori
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291245/
https://ncbi.nlm.nih.gov/pubmed/18241287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.03057.x
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