Absolute bioavailability of imidafenacin after oral administration to healthy subjects

AIMS: To investigate the absolute bioavailability of imidafenacin, a new muscarinic receptor antagonist, a single oral dose of 0.1 mg imidafenacin was compared with an intravenous (i.v.) infusion dose of 0.028 mg of the drug in healthy subjects. METHODS: Fourteen healthy male subjects, aged 21–45 ye...

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Detalhes bibliográficos
Main Authors: Ohno, Tomoya, Nakade, Susumu, Nakayama, Kazuki, Kitagawa, Junsaku, Ueda, Shinya, Miyabe, Hiroyuki, Masuda, Yuichi, Miyata, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291225/
https://ncbi.nlm.nih.gov/pubmed/18251758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02999.x
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