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Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs

Platinum drugs continue to be major chemotherapy drugs for cancer treatment. Nevertheless, acquired or intrinsic resistance to these compounds is common in human tumors. One important mechanism for this resistance is the avoidance of cells entering the apoptotic pathway. Nuclear factor-kappa B (NF-k...

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Hlavní autoři: Lagunas, Vilma Maldonado, Meléndez-Zajgla, Jorge
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291150/
https://ncbi.nlm.nih.gov/pubmed/18414584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/576104
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