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Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs

Platinum drugs continue to be major chemotherapy drugs for cancer treatment. Nevertheless, acquired or intrinsic resistance to these compounds is common in human tumors. One important mechanism for this resistance is the avoidance of cells entering the apoptotic pathway. Nuclear factor-kappa B (NF-k...

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Autors principals: Lagunas, Vilma Maldonado, Meléndez-Zajgla, Jorge
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291150/
https://ncbi.nlm.nih.gov/pubmed/18414584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/576104
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