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RTX cytotoxins recognize β(2) integrin receptors through N-linked oligosaccharides
Bordetella pertussis adenylate cyclase (AC) toxin–hemolysin (Hly) (CyaA, ACT, or AC-Hly) is a cytotoxin of the RTX (repeat in toxin) family. It delivers into target cells an AC domain that catalyzes uncontrolled conversion of ATP to cAMP, a key signaling molecule subverting phagocyte functions. CyaA...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291121/ https://ncbi.nlm.nih.gov/pubmed/18375764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711400105 |
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