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Tbx5-dependent pathway regulating diastolic function in congenital heart disease

At the end of every heartbeat, cardiac myocytes must relax to allow filling of the heart. Impaired relaxation is a significant factor in heart failure, but all pathways regulating the cardiac relaxation apparatus are not known. Haploinsufficiency of the T-box transcription factor Tbx5 in mouse and m...

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Detalhes bibliográficos
Main Authors: Zhu, Yonghong, Gramolini, Anthony O., Walsh, Mark A., Zhou, Yu-Qing, Slorach, Cameron, Friedberg, Mark K., Takeuchi, Jun K., Sun, Hui, Henkelman, R. Mark, Backx, Peter H., Redington, Andrew N., MacLennan, David H., Bruneau, Benoit G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291114/
https://ncbi.nlm.nih.gov/pubmed/18378906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801779105
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