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A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates
Regulated phosphorylation by protein tyrosine kinases (PTKs) such as c-Abl, is critical to cellular homeostasis. In turn, once deregulated as in the Chronic Myeloid Leukemia (CML) fusion protein Bcr-Abl, PTKs can promote cancer onset and progression. The dramatic success of the Bcr-Abl inhibitor ima...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291073/ https://ncbi.nlm.nih.gov/pubmed/18194660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2007.12.023 |
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