The liver pharmacological and xenobiotic gene response repertoire

We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound-treated rats. Thirty-four distinct signatures (classifiers) for pharmacological and toxicological end points can be identified. Just 200 genes are sufficient to classi...

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Autors principals: Natsoulis, Georges, Pearson, Cecelia I, Gollub, Jeremy, P Eynon, Barrett, Ferng, Joe, Nair, Ramesh, Idury, Radha, Lee, May D, Fielden, Mark R, Brennan, Richard J, Roter, Alan H, Jarnagin, Kurt
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290941/
https://ncbi.nlm.nih.gov/pubmed/18364709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.9
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