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A systems-level approach to mapping the telomere length maintenance gene circuitry

The ends of eukaryotic chromosomes are protected by telomeres, nucleoprotein structures that are essential for chromosomal stability and integrity. Understanding how telomere length is controlled has significant medical implications, especially in the fields of aging and cancer. Two recent systemati...

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Bibliographic Details
Main Authors: Shachar, Rafi, Ungar, Lior, Kupiec, Martin, Ruppin, Eytan, Sharan, Roded
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290934/
https://ncbi.nlm.nih.gov/pubmed/18319724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.13
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