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Disruptions in Golgi structure and membrane traffic in a conditional lethal mammalian cell mutant are corrected by epsilon-COP

The CHO cell temperature-sensitive mutant ldlF exhibits two defects in membrane traffic at the nonpermissive temperature (39.5 degrees C): rapid degradation of LDL receptors, possibly caused by endocytic missorting, and disruption of ER-through-Golgi transport. Here, we show that at 39.5 degrees C,...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290926/
https://ncbi.nlm.nih.gov/pubmed/8207054
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