Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot–Marie–Tooth 4B2-like peripheral neuropathy in mice

Charcot–Marie–Tooth disease type 4B (CMT4B) is a severe, demyelinating peripheral neuropathy characterized by slowed nerve conduction velocity, axon loss, and distinctive myelin outfolding and infolding. CMT4B is caused by recessive mutations in either myotubularin-related protein 2 (MTMR2; CMT4B1)...

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Bibliographic Details
Main Authors: Robinson, Fred L., Niesman, Ingrid R., Beiswenger, Kristina K., Dixon, Jack E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290800/
https://ncbi.nlm.nih.gov/pubmed/18349142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800742105
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