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Elucidating KChIP effects on Kv4.3 inactivation and recovery kinetics with a minimal KChIP2 isoform

Kv channel interacting proteins (KChIPs) are Ca(2+)-binding proteins with four EF-hands. KChIPs modulate Kv4 channel gating by slowing inactivation kinetics and accelerating recovery kinetics. Thus, KChIPs are believed to be important regulators of Kv4 channels underlying transient outward K(+) curr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Patel, Sangita P, Campbell, Donald L, Strauss, Harold C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290650/
https://ncbi.nlm.nih.gov/pubmed/12433945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.031856
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