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Excitation of rat colonic afferent fibres by 5-HT(3) receptors

The gastrointestinal tract contains most of the body's 5-hydroxytryptamine (5-HT) and releases large amounts after meals or exposure to toxins. Increased 5-HT release occurs in patients with irritable bowel syndrome (IBS) and their peak plasma 5-HT levels correlate with pain episodes. 5-HT(3) r...

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Autores principales: Hicks, Gareth A, Coldwell, Jonathan R, Schindler, Marcus, Bland Ward, Philip A, Jenkins, David, Lynn, Penny A, Humphrey, Patrick P A, Blackshaw, L Ashley
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290619/
https://ncbi.nlm.nih.gov/pubmed/12411529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.025452
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