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Presynaptic modulation of synaptic transmission by opioid receptor in rat subthalamic nucleus in vitro

Presynaptic modulation of synaptic transmission in rat subthalamic nucleus (STN) neurons was investigated using whole-cell patch-clamp recordings in brain slices. Evoked GABAergic inhibitory postsynaptic currents (IPSCs) were reversibly reduced by methionine enkephalin (ME) with an IC(50) value of 1...

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Bibliographic Details
Main Authors: Shen, Ke-Zhong, Johnson, Steven W
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290302/
https://ncbi.nlm.nih.gov/pubmed/12015431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013404
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