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Hypoxia inhibits human recombinant large conductance, Ca(2+)-activated K(+) (maxi-K) channels by a mechanism which is membrane delimited and Ca(2+) sensitive
Large conductance, Ca(2+)-activated K(+) (maxi-K) channel activity was recorded in excised, inside-out patches from HEK 293 cells stably co-expressing the α- and β-subunits of human brain maxi-K channels. At +50 mV, and in the presence of 300 nm [Formula: see text] , single channel activity was acut...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290273/ https://ncbi.nlm.nih.gov/pubmed/11986367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013888 |
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