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Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes

Nitric oxide (NO) can directly modulate cardiac contractility by accelerating relaxation and reducing diastolic tone. The intracellular mechanisms underlying these contractile effects are poorly understood. Here we investigate the role of cyclic GMP-dependent protein kinase (PKG) in the contractile...

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Autors principals: Layland, Joanne, Li, Jian-Mei, Shah, Ajay M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290258/
https://ncbi.nlm.nih.gov/pubmed/11956336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.014126
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