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Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes

Nitric oxide (NO) can directly modulate cardiac contractility by accelerating relaxation and reducing diastolic tone. The intracellular mechanisms underlying these contractile effects are poorly understood. Here we investigate the role of cyclic GMP-dependent protein kinase (PKG) in the contractile...

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Detalhes bibliográficos
Main Authors: Layland, Joanne, Li, Jian-Mei, Shah, Ajay M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290258/
https://ncbi.nlm.nih.gov/pubmed/11956336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.014126
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