Basolateral PAR-2 receptors mediate KCl secretion and inhibition of Na(+) absorption in the mouse distal colon

Proteinase-activated receptor-2 (PAR-2) may participate in epithelial ion transport regulation. Here we examined the effect of mouse activating peptide (mAP), a specific activator of PAR-2, on electrogenic transport of mouse distal colon using short-circuit current (I(SC)) measurements. Under steady...

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Autors principals: Cuffe, John E, Bertog, Marko, Velázquez-Rocha, Sara, Dery, Olivier, Bunnett, Nigel, Korbmacher, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290120/
https://ncbi.nlm.nih.gov/pubmed/11850514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013159
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