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Remodelling inactivation gating of Kv4 channels by KChIP1, a small-molecular-weight calcium-binding protein

Calcium-binding proteins dubbed KChIPs favour surface expression and modulate inactivation gating of neuronal and cardiac A-type Kv4 channels. To investigate their mechanism of action, Kv4.1 or Kv4.3 were expressed in Xenopus laevis oocytes, either alone or together with KChIP1, and the K(+) current...

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Autors principals: Beck, Edward J, Bowlby, Mark, An, W Frank, Rhodes, Kenneth J, Covarrubias, Manuel
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290090/
https://ncbi.nlm.nih.gov/pubmed/11826158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013127
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