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Binding mode prediction of conformationally restricted anandamide analogs within the CB(1 )receptor
BACKGROUND: CB(1 )cannabinoid receptors are G-protein coupled receptors for endocannabinoids including anandamide and 2-arachidonoylglycerol. Because these arachidonic acid metabolites possess a 20-carbon polyene chain as the alkyl terminal moiety, they are highly flexible with the potential to adop...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2289822/ https://ncbi.nlm.nih.gov/pubmed/18302793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-3-5 |
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