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Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice

The microRNA (miRNA) processing enzyme Dicer1 is required for zygotic and embryonic development, but the early embryonic lethality of Dicer1 null alleles in mice has limited our ability to address the role of Dicer1 in normal mouse growth and development. To address this question, we used a mouse mu...

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Detalhes bibliográficos
Main Authors: Otsuka, Motoyuki, Zheng, Min, Hayashi, Masaaki, Lee, Jing-Dwan, Yoshino, Osamu, Lin, Shengcai, Han, Jiahuai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289794/
https://ncbi.nlm.nih.gov/pubmed/18398510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33680
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