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Activation of the alpha subunit of Gs in intact cells alters its abundance, rate of degradation, and membrane avidity

Binding of GTP induces alpha subunits of heterotrimeric G proteins to take on an active conformation, capable of regulating effector molecules. We expressed epitope-tagged versions of the alpha subunit (alpha s) of Gs in genetically alpha s-deficient S49 cyc- cells. Addition of a hemagglutinin (HA)...

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Bibliografski detalji
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1992
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289737/
https://ncbi.nlm.nih.gov/pubmed/1280272
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