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Selective inhibition of protein targeting to the apical domain of MDCK cells by brefeldin A

Dipeptidyl peptidase IV (DPPIV) is mainly vectorially targeted to the apical surface in MDCK cells. BFA was found to abolish the apical targeting of DPPIV. This BFA effect could be achieved under conditions where the ER to Golgi transport and the total surface expression of DPPIV were essentially un...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289512/
https://ncbi.nlm.nih.gov/pubmed/1352300
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