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Requirement of the integrin beta 3 subunit for carcinoma cell spreading or migration on vitronectin and fibrinogen

FG human pancreatic carcinoma cells use integrin alpha v beta 5 as their primary vitronectin receptor since they fail to express integrin alpha v beta 3. These cells are unable to form focal contacts, spread, or migrate on vitronectin but readily do so on collagen in a beta 1 integrin-dependent mann...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289489/
https://ncbi.nlm.nih.gov/pubmed/1374415
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