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Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210

The mouse FT210 cell line is a temperature-sensitive cdc2 mutant. FT210 cells are found to arrest specifically in G2 phase and unlike many alleles of cdc2 and cdc28 mutants of yeasts, loss of p34cdc2 at the nonpermissive temperature has no apparent effect on cell cycle progression through the G1 and...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1992
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289476/
https://ncbi.nlm.nih.gov/pubmed/1533642
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