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Are the conserved sequences in segment 1 of gelsolin important for binding actin?

The minimal region required for actin binding in the smallest of the three domains of gelsolin (termed Segment 1 or S1) was previously defined by deletion mutagenesis as residues 37-126. Further analysis of NH2-terminal deletions here redefines the minimal functional core as residues 41-126. Amino a...

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Podrobná bibliografie
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289352/
https://ncbi.nlm.nih.gov/pubmed/1310993
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