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Direct proof that the primary site of action of cytochalasin on cell motility processes is actin

We have previously described the isolation of a mutant KB cell (Cyt 1 mutant) resistant to the cytotoxic effect of cytochalasin B (CB). The Cyt 1 mutant carries an altered form of beta-actin (beta'-actin) and lacks normal beta-actin (Toyama, S., and S. Toyama. 1984. Cell. 37:609- 614). Increase...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1992
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289332/
https://ncbi.nlm.nih.gov/pubmed/1734024
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