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Thrombin neutralizes plasminogen activator inhibitor 1 (PAI-1) that is complexed with vitronectin in the endothelial cell matrix

Vitronectin endows plasminogen activator inhibitor 1 (PAI-1), the fast- acting inhibitor of both tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), with additional thrombin inhibitory properties. In view of the apparent association between PAI- 1 and vitronecti...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2289214/
https://ncbi.nlm.nih.gov/pubmed/1721912
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