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Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin
Alpha-actinin can be proteolytically cleaved into major fragments of 27 and 53 kD using the enzyme thermolysin. The 27-kD fragment contains an actin-binding site and we have recently shown that the 53-kD fragment binds to the cytoplasmic domain of beta 1 integrin in vitro (Otey, C. A., F. M. Pavalko...
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| Formato: | Artigo |
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| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1991
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2289090/ https://ncbi.nlm.nih.gov/pubmed/1907287 |
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