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Mastoparan, a novel mitogen for Swiss 3T3 cells, stimulates pertussis toxin-sensitive arachidonic acid release without inositol phosphate accumulation
Mastoparan, a basic tetradecapeptide isolated from wasp venom, is a novel mitogen for Swiss 3T3 cells. This peptide induced DNA synthesis in synergy with insulin in a concentration-dependent manner; half- maximum and maximum responses were achieved at 14 and 17 microM, respectively. Mastoparan also...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2288979/ https://ncbi.nlm.nih.gov/pubmed/1709171 |
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