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An internally positioned signal can direct attachment of a glycophospholipid membrane anchor

All known glycophosphatidylinositol (GPI)-anchored membrane proteins contain a COOH-terminal hydrophobic domain necessary for signalling anchor attachment. To examine the requirement that this signal be at the COOH terminus of the protein, we constructed a chimeric protein, DAFhGH, in which human gr...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288913/
https://ncbi.nlm.nih.gov/pubmed/1706725
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