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Fragmentation of Multiply-Charged Intact Protein Ions Using MALDI TOF-TOF Mass Spectrometry

Top down proteomics in a TOF-TOF instrument was further explored by examining the fragmentation of multiply charged precursors ions generated by matrix-assisted laser desorption ionization. Evaluation of sample preparation conditions allowed selection of solvent/matrix conditions and sample depositi...

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Detalhes bibliográficos
Main Authors: Liu, Zhaoyang, Schey, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288703/
https://ncbi.nlm.nih.gov/pubmed/17693096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2007.06.006
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