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The Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolution

Hedgehog signaling is an important component of cell-cell communication during bilaterian development, and abnormal Hedgehog signaling contributes to disease and birth defects. Hedgehog genes are composed of a ligand (“hedge”) domain and an autocatalytic intein (“hog”) domain. Hedgehog (hh) ligands...

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Autors principals: Matus, David Q., Magie, Craig, Pang, Kevin, Martindale, Mark Q, Thomsen, Gerald H.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288667/
https://ncbi.nlm.nih.gov/pubmed/18068698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.09.032
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