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Source–sink dynamics shape the evolution of antibiotic resistance and its pleiotropic fitness cost

Understanding the conditions that favour the evolution and maintenance of antibiotic resistance is the central goal of epidemiology. A crucial feature explaining the adaptation to harsh, or ‘sink’, environments is the supply of beneficial mutations via migration from a ‘source’ population. Given tha...

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Autors principals: Perron, Gabriel G, Gonzalez, Andrew, Buckling, Angus
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288555/
https://ncbi.nlm.nih.gov/pubmed/17650474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2007.0640
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