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The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active
TRPV3 is a non-selective cation channel activated by warm to hot temperatures. In rodents, TRPV3 is highly expressed in basal keratinocytes of skin and oral/nasal epithelia. TRPV3 knockout mice showed impaired responses to innocuous and noxious heat but otherwise normal appearance and reactions to m...
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| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2287378/ https://ncbi.nlm.nih.gov/pubmed/17706768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2007.06.004 |
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