Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis

NmrA is a negative transcription-regulating protein that binds to the C-terminal region of the GATA transcription-activating protein AreA. The proposed molecular mechanism of action for NmrA is to inhibit AreA binding to its target promoters. In contrast to this proposal, we report that a C-terminal...

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Xehetasun bibliografikoak
Egile Nagusiak: Lamb, Heather K., Ren, Jingshan, Park, Alison, Johnson, Christopher, Leslie, Kris, Cocklin, Simon, Thompson, Paul, Mee, Christopher, Cooper, Alan, Stammers, David K., Hawkins, Alastair R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2004
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2287298/
https://ncbi.nlm.nih.gov/pubmed/15537757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04958904
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