Rarity of Somatic Mutation and Frequency of Normal Sequence Variation Detected in Sporadic Colon Adenocarcinoma Using High-Throughput cDNA Sequencing

We performed high-throughput cDNA sequencing in colorectal adenocarcinoma and matching normal colorectal epithelium. All six hundred three genes in the UCSC database that were expressed in colon cancers and contained open reading frames of 1000 nucleotides or less were selected for study (total base...

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Detalhes bibliográficos
Main Authors: Kan, Takatsugu, Paun, Bogdan C., Mori, Yuriko, Sato, Fumiaki, Jin, Zhe, Hamilton, James P., Ito, Tetsuo, Cheng, Yulan, David, Stefan, Olaru, Alexandru V., Yang, Jian, Agarwal, Rachana, Abraham, John M., Meltzer, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2009
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2287164/
https://ncbi.nlm.nih.gov/pubmed/18389087
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