CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells

AIDS is characterized by a progressive decrease of CD4(+) helper T lymphocytes. Destruction of these cells may involve programmed cell death, apoptosis. It has previously been reported that apoptosis can be induced even in noninfected cells by HIV-1 gp120 and anti-gp120 antibodies. HIV-1 gp120 binds...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Berndt, Christina, Möpps, Barbara, Angermüller, Sabine, Gierschik, Peter, Krammer, Peter H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12556
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