An evolutionary route to xylanase process fitness

Directed evolution technologies were used to selectively improve the stability of an enzyme without compromising its catalytic activity. In particular, this article describes the tandem use of two evolution strategies to evolve a xylanase, rendering it tolerant to temperatures in excess of 90°C. A l...

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Hauptverfasser: Palackal, Nisha, Brennan, Yali, Callen, Walter N., Dupree, Paul, Frey, Gerhard, Goubet, Florence, Hazlewood, Geoffrey P., Healey, Shaun, Kang, Young E., Kretz, Keith A., Lee, Edd, Tan, Xuqiu, Tomlinson, Geoffery L., Verruto, John, Wong, Vicky W.K., Mathur, Eric J., Short, Jay M., Robertson, Dan E., Steer, Brian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286715/
https://ncbi.nlm.nih.gov/pubmed/14718652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03333504
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