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Automated selection of positions determining functional specificity of proteins by comparative analysis of orthologous groups in protein families

The increasing volume of genomic data opens new possibilities for analysis of protein function. We introduce a method for automated selection of residues that determine the functional specificity of proteins with a common general function (the specificity-determining positions [SDP] prediction metho...

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Detalhes bibliográficos
Main Authors: Kalinina, Olga V., Mironov, Andrey A., Gelfand, Mikhail S., Rakhmaninova, Aleksandra B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2286703/
https://ncbi.nlm.nih.gov/pubmed/14739328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03191704
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