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The folding landscape of Streptomyces griseus protease B reveals the energetic costs and benefits associated with evolving kinetic stability
Like most extracellular bacterial proteases, Streptomyces griseus protease B (SGPB) and α-lytic protease (αLP) are synthesized with covalently attached pro regions necessary for their folding. In this article, we characterize the folding free energy landscape of SGPB and compare it to the folding la...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2004
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2286692/ https://ncbi.nlm.nih.gov/pubmed/14718653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03336804 |
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